TODAY
The University of Western Ontario
DEPARTMENT OF PHYSICS AND ASTRONOMY
PHYSICS & ASTRONOMY COLLOQUIUM
Date: Thursday, 26th January 2011
Time: 1:30 p.m.
Location: Physics & Astronomy Seminar Room 22
Dr. Blaine Chronik
Physics & Astronomy Department
The University of Western Ontario
“Variable fields in MRI: progress, opportunities, and challenges”
ABSTRACT
Over the past 8 years or so, we have worked on Magnetic Resonance Imaging methods and technology which are distinguished because of their focus on the use of rapidly varying, strong magnetic fields.
Our approach has evolved, from what was purely “laboratory,” preclinical implementation, to our current efforts which focus on systems for use in clinical MR scanners.
In this talk, I will describe a new method of MRI in which we strive to produce very specific MR image contrast due to the presence of a chemical contrast-agent, only when that agent is bound to target molecules of interest. This represents a means to achieve contrast specificity in MRI that has not been previously available. The method is called “dreMR”: delta relaxation enhanced MR (reference: Magn Reson in Med, 61(4):796-8002 (2009)). This technique requires a major change to the MRI system architecture – specifically, the ability to vary the main magnetic field strength as a function of time. I will review the concept behind the method, our preclinical technological implementation, and we will discuss the applicability of the method for human-scale subjects. Along the way, we will also review the wider range of MR system developments we've worked on, and some of our future projects.
Coffee & cookies will be provided.